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  1. Content type: Research

    Measuring how gene expression changes in the course of an experiment assesses how an organism responds on a molecular level. Sequencing of RNA molecules, and their subsequent quantification, aims to assess glo...

    Authors: Bork A. Berghoff, Torgny Karlsson, Thomas Källman, E. Gerhart H. Wagner and Manfred G. Grabherr

    Citation: BioData Mining 2017 10:30

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  2. Content type: Methodology

    The modeling of genetic interactions within a cell is crucial for a basic understanding of physiology and for applied areas such as drug design. Interactions in gene regulatory networks (GRNs) include effects ...

    Authors: Mina Moradi Kordmahalleh, Mohammad Gorji Sefidmazgi, Scott H. Harrison and Abdollah Homaifar

    Citation: BioData Mining 2017 10:29

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  3. Content type: Short Report

    BarraCUDA is an open source C program which uses the BWA algorithm in parallel with nVidia CUDA to align short next generation DNA sequences against a reference genome. Recently its source code was optimised u...

    Authors: W. B. Langdon and Brian Yee Hong Lam

    Citation: BioData Mining 2017 10:28

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  4. Content type: Research

    Non-coding RNA (ncRNA) are small non-coding sequences involved in gene expression regulation of many biological processes and diseases. The recent discovery of a large set of different ncRNAs with biologically...

    Authors: Antonino Fiannaca, Massimo La Rosa, Laura La Paglia, Riccardo Rizzo and Alfonso Urso

    Citation: BioData Mining 2017 10:27

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  5. Content type: Research

    The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits...

    Authors: Emily R. Holzinger, Shefali S. Verma, Carrie B. Moore, Molly Hall, Rishika De, Diane Gilbert-Diamond, Matthew B. Lanktree, Nathan Pankratz, Antoinette Amuzu, Amber Burt, Caroline Dale, Scott Dudek, Clement E. Furlong, Tom R. Gaunt, Daniel Seung Kim, Helene Riess…

    Citation: BioData Mining 2017 10:25

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  6. Content type: Software article

    Recently we surveyed the dark-proteome, i.e., regions of proteins never observed by experimental structure determination and inaccessible to homology modelling. Surprisingly, we found that most of the dark pro...

    Authors: Nelson Perdigão, Agostinho C. Rosa and Seán I. O’Donoghue

    Citation: BioData Mining 2017 10:24

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  7. Content type: Software article

    Refinement of candidate gene lists to select the most promising candidates for further experimental verification remains an essential step between high-throughput exploratory analysis and the discovery of spec...

    Authors: Artem Lysenko, Keith Anthony Boroevich and Tatsuhiko Tsunoda

    Citation: BioData Mining 2017 10:22

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  8. Content type: Methodology

    Large-scale genetic studies of common human diseases have focused almost exclusively on the independent main effects of single-nucleotide polymorphisms (SNPs) on disease susceptibility. These studies have had ...

    Authors: Jason H. Moore, Peter C. Andrews, Randal S. Olson, Sarah E. Carlson, Curt R. Larock, Mario J. Bulhoes, James P. O’Connor, Ellen M. Greytak and Steven L. Armentrout

    Citation: BioData Mining 2017 10:19

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  9. Content type: Methodology

    Genetic studies for complex diseases have predominantly discovered main effects at individual loci, but have not focused on genomic and environmental contexts important for a phenotype. Gene Set Enrichment Ana...

    Authors: Vinicius Tragante, Johannes M. I. H. Gho, Janine F. Felix, Ramachandran S. Vasan, Nicholas L. Smith, Benjamin F. Voight, Colin Palmer, Pim van der Harst, Jason H. Moore and Folkert W. Asselbergs

    Citation: BioData Mining 2017 10:18

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  10. Content type: Short report

    Every year around 300 Gl of vinasse, a by-product of ethanol distillation in sugarcane mills, are flushed into more than 9 Mha of sugarcane cropland in Brazil. This practice links fermentation waste management...

    Authors: Lucas P. P. Braga, Rafael F. Alves, Marina T. F. Dellias, Acacio A. Navarrete, Thiago O. Basso and Siu M. Tsai

    Citation: BioData Mining 2017 10:17

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  11. Content type: Research

    Any family of learning machines can be combined into a single learning machine using various methods with myriad degrees of usefulness.

    Authors: Bilguunzaya Battogtokh, Majid Mojirsheibani and James Malley

    Citation: BioData Mining 2017 10:16

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  12. Content type: Methodology

    Reverse engineering of gene regulatory networks (GRNs) from gene expression data is a classical challenge in systems biology. Thanks to high-throughput technologies, a massive amount of gene-expression data ha...

    Authors: Ngoc C. Pham, Benjamin Haibe-Kains, Pau Bellot, Gianluca Bontempi and Patrick E. Meyer

    Citation: BioData Mining 2017 10:15

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  13. Content type: Research

    Large number of features are extracted from protein crystallization trial images to improve the accuracy of classifiers for predicting the presence of crystals or phases of the crystallization process. The exc...

    Authors: Madhav Sigdel, Imren Dinc, Madhu S. Sigdel, Semih Dinc, Marc L. Pusey and Ramazan S. Aygun

    Citation: BioData Mining 2017 10:14

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  14. Content type: Methodology

    A computational evolution system (CES) is a knowledge discovery engine that can identify subtle, synergistic relationships in large datasets. Pareto optimization allows CESs to balance accuracy with model comp...

    Authors: Nathaniel M. Crabtree, Jason H. Moore, John F. Bowyer and Nysia I. George

    Citation: BioData Mining 2017 10:13

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  15. Content type: Methodology

    In metabolomics, thousands of substances can be detected in a single assay. This capacity motivates the development of metabolomics testing, which is currently a very promising option for improving laboratory ...

    Authors: Petr G. Lokhov, Dmitri L. Maslov, Oleg N. Kharibin, Elena E. Balashova and Alexander I. Archakov

    Citation: BioData Mining 2017 10:10

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  16. Content type: Methodology

    Genetic predispositions to diseases populate the noncoding regions of the human genome. Delineating their functional basis can inform on the mechanisms contributing to disease development. However, this remain...

    Authors: Musaddeque Ahmed, Richard C. Sallari, Haiyang Guo, Jason H. Moore, Housheng Hansen He and Mathieu Lupien

    Citation: BioData Mining 2017 10:9

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  17. Content type: Methodology

    Capturing complete medical knowledge is challenging-often due to incomplete patient Electronic Health Records (EHR), but also because of valuable, tacit medical knowledge hidden away in physicians’ experiences...

    Authors: Hossein Mohammadhassanzadeh, William Van Woensel, Samina Raza Abidi and Syed Sibte Raza Abidi

    Citation: BioData Mining 2017 10:7

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  18. Content type: Research

    Aldolase A (ALDOA) is one of the glycolytic enzymes primarily found in the developing embryo and adult muscle. Recently, a new role of ALDOA in several cancers has been proposed. However, the underlying mechan...

    Authors: Fan Zhang, Jie-Diao Lin, Xiao-Yu Zuo, Yi-Xuan Zhuang, Chao-Qun Hong, Guo-Jun Zhang, Xiao-Jiang Cui and Yu-Kun Cui

    Citation: BioData Mining 2017 10:6

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Page 2 of 12

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