| |
SLE
|
RA
| | |
95% CI
|
|---|
|
HLA alleles
|
count
|
%
|
count
|
%
|
p value
|
OR
|
lower
|
upper
|
|
DQA1*01:02
|
877
|
20.0
|
655
|
15.7
|
1.28E-07
|
1.35
|
1.21
|
1.51
|
|
DQA1*01:03
|
516
|
11.8
|
365
|
8.7
|
3.13E-06
|
1.40
|
1.21
|
1.61
|
|
DQA1*03:01
|
252
|
5.8
|
342
|
8.2
|
1.07E-05
|
0.69
|
0.58
|
0.81
|
|
DQA1*03:02
|
662
|
15.1
|
736
|
17.5
|
1.99E-03
|
0.83
|
0.74
|
0.94
|
|
DQA1*03:03
|
300
|
6.9
|
598
|
14.3
|
2.84E-29
|
0.44
|
0.38
|
0.51
|
|
DQA1*05:01
|
420
|
9.6
|
181
|
4.3
|
1.48E-21
|
2.35
|
1.96
|
2.81
|
|
DQA1*05:05
|
437
|
10.0
|
401
|
9.6
|
5.36E-01
|
1.05
|
0.91
|
1.21
|
|
DQA1*06:01
|
312
|
7.3
|
387
|
9.3
|
3.35E-04
|
0.75
|
0.64
|
0.88
|
|
DQB1*02:01
|
414
|
9.5
|
178
|
4.3
|
2.44E-21
|
2.35
|
1.96
|
2.82
|
|
DQB1*03:01
|
833
|
19.0
|
858
|
20.6
|
8.55E-02
|
0.91
|
0.82
|
1.01
|
|
DQB1*03:02
|
243
|
5.6
|
321
|
7.7
|
7.61E-05
|
0.71
|
0.6
|
0.84
|
|
DQB1*03:03
|
684
|
15.6
|
763
|
18.2
|
1.26E-03
|
0.83
|
0.74
|
0.93
|
|
DQB1*04:01
|
268
|
6.1
|
554
|
13.2
|
5.20E-29
|
0.43
|
0.37
|
0.5
|
|
DQB1*05:02
|
515
|
11.7
|
431
|
10.3
|
3.10E-02
|
1.16
|
1.01
|
1.33
|
|
DQB1*06:01
|
647
|
14.8
|
468
|
11.2
|
7.90E-07
|
1.38
|
1.21
|
1.56
|
|
DQB1*06:02
|
248
|
5.7
|
167
|
4.0
|
3.14E-04
|
1.44
|
1.18
|
1.77
|
|
DRB1*03:01
|
415
|
9.5
|
179
|
4.3
|
2.87E-21
|
2.34
|
1.96
|
2.81
|
|
DRB1*04:05
|
287
|
6.6
|
607
|
14.4
|
2.51E-33
|
0.41
|
0.36
|
0.48
|
|
DRB1*08:03
|
484
|
11.1
|
336
|
8.0
|
2.00E-06
|
1.42
|
1.23
|
1.65
|
|
DRB1*09:01
|
665
|
15.2
|
750
|
17.8
|
6.55E-04
|
0.82
|
0.73
|
0.92
|
|
DRB1*11:01
|
291
|
6.6
|
296
|
7.1
|
4.34E-01
|
0.94
|
0.79
|
1.11
|
|
DRB1*12:02
|
321
|
7.3
|
387
|
9.3
|
1.28E-03
|
0.78
|
0.67
|
0.91
|
|
DRB1*15:01
|
476
|
10.9
|
341
|
8.2
|
1.82E-05
|
1.37
|
1.19
|
1.59
|
|
DRB1*16:02
|
310
|
7.1
|
246
|
5.9
|
2.42E-02
|
1.22
|
1.03
|
1.45
|
- By Pearson’s chi-squared test. RA as a reference group. HLA: human leukocyte antigen; SLE: systemic lupus erythematosus; RA: rheumatoid arthritis; OR: odds ratio; CI: confidence interval
