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Table 2 The main targets of Xiaochaihu decoction in the treatment of NAFLD

From: Network pharmacology reveals the multiple mechanisms of Xiaochaihu decoction in the treatment of non-alcoholic fatty liver disease

UniProtKB

Target

Degree

P35354

PTGS2

161

P03372

ESR1

98

P35228

NOS2

93

P37231

PPARG

90

P07477

PRSS1

88

P07550

ADRB2

73

P49841

GSK3B

67

P19793

RXRA

62

Q15788

NCOA1

45

P22303

ACHE

38

  1. Notes: PTGS2 Prostaglandin-endoperoxide Synthase 2, ESR1 Estrogen Receptor 1, NOS2 Nitric Oxide Synthase 2, PPARG Peroxisome Proliferator Activated Receptor Gamma, PRSS1 serine protease 1, ADRB2 Adrenoceptor Beta 2, GSK3B Glycogen Synthase Kinase 3 Beta, RXRA Retinoid X Receptor Alpha, NCOA1 Nuclear Receptor Coactivator 1, ACHE Acetylcholinesterase