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Table 2 The main targets of Xiaochaihu decoction in the treatment of NAFLD

From: Network pharmacology reveals the multiple mechanisms of Xiaochaihu decoction in the treatment of non-alcoholic fatty liver disease

UniProtKB Target Degree
P35354 PTGS2 161
P03372 ESR1 98
P35228 NOS2 93
P37231 PPARG 90
P07477 PRSS1 88
P07550 ADRB2 73
P49841 GSK3B 67
P19793 RXRA 62
Q15788 NCOA1 45
P22303 ACHE 38
  1. Notes: PTGS2 Prostaglandin-endoperoxide Synthase 2, ESR1 Estrogen Receptor 1, NOS2 Nitric Oxide Synthase 2, PPARG Peroxisome Proliferator Activated Receptor Gamma, PRSS1 serine protease 1, ADRB2 Adrenoceptor Beta 2, GSK3B Glycogen Synthase Kinase 3 Beta, RXRA Retinoid X Receptor Alpha, NCOA1 Nuclear Receptor Coactivator 1, ACHE Acetylcholinesterase
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