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Fig. 6 | BioData Mining

Fig. 6

From: RNA-sequence data normalization through in silico prediction of reference genes: the bacterial response to DNA damage as case study

Fig. 6

Validation on three eukaryotic data sets. a Dendrograms based on the TMM, DESeq2 and moose 2 methods on data from human glioblastoma cells [29] show that moose 2 groups all samples correctly, whereas DESeq2 and TMM place one sample incorrectly. b On data from primary airway epithelial cells [30], all three methods result in the same sample grouping, with one outlier sample. c On data from nine dog tissues [31] for non-coding, single exon genes, moose 2 and DESeq2 correctly group the replicates and related tissues (heart, muscle)

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BioData Mining

ISSN: 1756-0381