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Table 1 Additional metrics used for integrative analysis example and informal descriptions of what properties they capture

From: Arete – candidate gene prioritization using biological network topology with additional evidence types

Metric name Property captured
Eccentricity Overall remoteness from all other nodes
Transitivity Density of interlinks among immediate neighbors
Betweenness Network “choke points” with high proportion of shortest paths going through them
Tissue-specific expression Ubiquitous versus tissue-specific expression
k-core number Location in a dense core versus network periphery