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Table 1 Additional metrics used for integrative analysis example and informal descriptions of what properties they capture

From: Arete – candidate gene prioritization using biological network topology with additional evidence types

Metric name

Property captured

Eccentricity

Overall remoteness from all other nodes

Transitivity

Density of interlinks among immediate neighbors

Betweenness

Network “choke points” with high proportion of shortest paths going through them

Tissue-specific expression

Ubiquitous versus tissue-specific expression

k-core number

Location in a dense core versus network periphery

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BioData Mining

ISSN: 1756-0381