Revealing third-order interactions through the integration of machine learning and entropy methods in genomic studies

Table 1 Test statistics and permutation testing results for GenADA dataset

SNP1	SNP2	SNP3	T_IG	P-value	Permutation p-value	Gene1	Gene2	Gene3
rs17793957	rs605928	rs9911460	8.50	0.003	0.001	FBLN2	ADAM10	NPLOC4
rs7045548	rs1795977	rs11652714	8.25	0.004	0.001	-	-	-
rs1879019	rs17081694	rs605928	6.65	0.009	0.002	ADAM10	-	-
rs1608169	rs11862388	rs16993582	7.14	0.007	0.003	-	-	RUNX1
rs4895529	rs9314604	rs17081694	8.47	0.003	0.006	NHSL1	ANGPT2 / MCPH1	-
rs17067596	rs9314604	rs17081694	8.46	0.003	0.008	NHSL1	-
rs10050568	rs2978012	rs6098412	7.76	0.005	0.015	SPOCK1	ST3GAL1	-
rs1879019	rs1519959	rs136687	8.48	0.003	0.036	-	-	PHF21B

ISSN: 1756-0381