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Table 3 Performance of combining different classifiers in the first layer

From: 6mA-StackingCV: an improved stacking ensemble model for predicting DNA N6-methyladenine site

First- layer classifiers

ACC (95%CI)

AUC (95%CI)

XGBoost, Gradient boosting, LightGBM, random forest, logistic regression, decision tree

0.9484 (0.9440–0.9528)

0.9588 (0.9551–0.9624)

XGBoost, Gradient boosting, LightGBM, random forest, logistic regression

0.9486 (0.9444–0.9527)

0.9589 (0.9557–0.9622)

XGBoost, Gradient boosting, LightGBM, random forest

0.9487 (0.9446–0.9529)

0.9605 (0.9573–0.9637)

XGBoost, Gradient boosting, LightGBM

0.9488 (0.9445–0.9531)

0.9616 (0.9586–0.9646)

XGBoost, Gradient boosting

0.9469 (0.9430–0.9509)

0.9582 (0.9545–0.9620)

XGBoost, LightGBM

0. 9477 (0.9438–0.9517)

0.9605 (0.9583–0.9627)

Gradient boosting, LightGBM

0.9449 (0.9409–0.9490)

0.9597 (0.9572–0.9621)