Table 8 Time complexity for feature selection methods and subtyping methods

Subtyping Identification Methods without FS

CC

PINS

NMF

ICB

SNF

NEMO

AML

5.18

20.64

1130.33

870.40

2.19

2.18

GBM

37.29

131.21

1982.45

870.40

6.00

5.87

BIC

53.33

95.90

7573.64

1334.64

9.76

9.25

COAD

8.83

33.84

1809.96

1058.59

1.41

1.36

Feature Selection Methods

MED

VAR

MAD

DIP

mRMR

MCFS

COAD

500

0.87

0.78

1.15

7.43

0.53

30,078.44

2000

0.86

0.18

1.15

5.49

2.05

30,078.44

BRCA

500

2.71

0.90

3.10

8.12

1.53

108,000.00

2000

1.06

1.53

2.40

8.64

3.72

108,000.00