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Table 2 Comorbidities and risk factors dissected by subgroups after AKI detection

From: Algorithm-based detection of acute kidney injury according to full KDIGO criteria including urine output following cardiac surgery: a descriptive analysis

  

Total cohort

Disease group

AKI stages

Comorbidities/risk factors

ICD10

N

%

AKI (%)

N = 11664

No AKI (%)

N = 3516

p-valuea

AKI 1 (%)

N = 2848

AKI 2 (%)

N = 5689

AKI 3 (%)

N = 3127

Chronic ischaemic heart disease

I25

10,678

50.7

71.6

66.1

< 0.001

71.6

73.1

68.9

Essential (primary) hypertension

I10

8693

41.3

57.5

56.6

0.361

55.2

59.0

56.7

Disorders of lipoprotein metabolism and other lipidaemias

E78

4425

21.0

28.6

31.0

0.007

29.4

29.1

27.0

Unspecified diabetes mellitus

E14

3621

17.2

24.9

20.3

< 0.001

21.9

25.1

27.4

Nonrheumatic aortic valve disorders

I35

3458

16.4

23.4

20.8

0.002

23.1

23.5

23.3

Nonrheumatic mitral valve disorders

I34

2661

12.6

17.2

18.8

0.027

18.2

16.3

17.8

Atrial fibrillation and flutter

I48

2625

12.5

19.1

11.4

< 0.001

15.9

19.4

21.4

Chronic kidney disease

N18

1622

7.7

12.3

5.5

< 0.001

10.2

10.0

18.3

Obesity

E66

1533

7.3

11.0

7.1

< 0.001

7.2

12.1

12.4

Atherosclerosis

I70

1204

5.7

8.2

7.1

0.033

8.0

7.9

9.0

Other chronic obstructive pulmonary disease

J44

878

4.2

6.1

4.8

0.006

5.9

6.2

6.0

Sleep disorders

G47

548

2.6

3.9

2.6

< 0.001

2.9

4.2

4.2

Acute and subacute endocarditis

I33

508

2.4

3.7

2.2

< 0.001

2.7

3.1

5.7

Aortic aneurysm and dissection

I71

316

1.5

2.4

0.9

< 0.001

1.9

2.1

3.5

  1. Note that except for total cohort, only patients with at least one considered comorbidity or risk factor are considered. Percentages are computed with N of each subgroup
  2. aPearson’s Chi-squared test