Table 9 Comparison of methods using the DREAM Challenge dataset
From: Prediction of synergistic drug combinations using PCA-initialized deep learning
Method | MSE | RMSE | Pearson’s r |
|---|---|---|---|
PCA + Deep learning | 279.30 ± 47.62 | 16.71 ± 1.30 | 0.56 ± 0.02 |
PCA + XGBoost | 376.14 ± 51.27 | 19.39 ± 1.46 | 0.43 ± 0.04 |
PCA + Random Forests | 395.18 ± 54.39 | 19.87 ± 1.28 | 0.39 ± 0.02 |
PCA + Elastic net | 501.29 ± 58.37 | 22.39 ± 1.58 | 0.31 ± 0.03 |