Fig. 5

The RWR scores for the hidden and unknown gene-annotation connections (faceted by the amount of sparsity). When known connections are hidden, RWR tends to give higher scores than when connections are unknown, suggesting that RWR can discover real gene-annotation relationships. Note that GO is an incomplete database: the absence of a gene-annotation connection is not the evidence of absence. For this reason, we do know whether the high scoring “Unknown” connections are false positives or previously undiscovered connections. All t-tests comparing “Hidden” and “Unknown” connections have p<10⁻¹⁵