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Table 2 KEGG pathway analysis of Eucommia ulmoides (EU)-Radix Achyranthis Bidentatae (RAB) in treating Osteoarthritis (OA) network

From: Application of network pharmacology and molecular docking to elucidate the potential mechanism of Eucommia ulmoides-Radix Achyranthis Bidentatae against osteoarthritis

No. Pathwy ID Pathway name P value FDR Count Gene name
1 04210 Apoptosis 7.20E-14 2.70E-12 15 RELA,BCL2,FOS,CASP9,CASP3,NFKBIA,CASP8,BIRC5,PARP1,CTSD,IKBKB,MAPK8,CASP7,CYCS,MCL1
2 04151 PI3K-Akt signaling pathway 5.82E-08 2.05E-07 15 RELA,EGFR,VEGFA,CCND1,BCL2,CASP9,IL6,PRKCA,ERBB2,MYC,NOS3,IGF2,IKBKB,GSK3B,MCL1
3 04668 TNF signaling pathway 2.09E-12 1.88E-11 13 RELA,FOS,IL6,CASP3,NFKBIA,CASP8,ICAM1,SELE,VCAM1,IRF1,IKBKB,MAPK8,CASP7
4 04010 MAPK signaling pathway 3.31E-07 8.64E-07 13 RELA,EGFR,VEGFA,FOS,CASP3,ELK1,PRKCA,ERBB2,MYC,HSPB1,IGF2,IKBKB,MAPK8
5 04657 IL-17 signaling pathway 1.99E-09 1.08E-08 10 RELA,FOS,IL6,CASP3,NFKBIA,CASP8,IKBKB,MAPK8,GSK3B,FOSL1
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