Fig. 6
From: Revisiting the use of graph centrality models in biological pathway analysis
Comparison of the cumulative density between lethal genes and normal (non-lethal) genes. The data points represent the quantile-scores calculated based on normalized centrality (Formula 23) across all pathways. Each panel includes the p-value of Kolmogorov-Smirnov test for the hypothesis of the CDF of lethal genes being below that of the normal genes. The panels show that lethal genes tend to have higher centrality values according to some of the models, including Source/Sink PageRank and Source/Sink Laplacian