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Fig. 3 | BioData Mining

Fig. 3

From: Integrative analysis of genetic and epigenetic profiling of lung squamous cell carcinoma (LSCC) patients to identify smoking level relevant biomarkers

Fig. 3

Circos analysis of global methylation status differences between high and low intensive smoking LSCC patients. The outer layer represents CpG islands heatmap. Red color represents CpG islands are hyper-methylated. Green color represents CpG islands are hypo-methylated. The middle layer represents scatter plot of single CpG site. Each dot represents a significant different DNA methylation changes, with p-value associated at Y-axis. The inner layer of circular plot is top 100 genes with the largest betafc value in DNA methylation changes of CpG islands

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