
A

B

C

D


pvalue

1.06E282

4.98E225

1.80E319

0

Chisquare

1323.14

1056.65

1492.95

9013.65

Degree of freedom

6

6

6

6

 Each column indicates the result of a separate chisquared test (i.e., pvalue, statistics, and degree of freedom). The labels “A”, “B”, “C”, and “D” designate which comethylation patterns/states are compared in the test. For example, “A” means that the chisquared test compares the percentage occurrence of all state pairs beginning with state “A” (AA, AB, AC, and AD). The input used for the chisquared test of methylation state “A” is the counts in the row A of samples 1, 2, 3 in Table 2 (that is, the three rows starting with these numbers 159,513, 170,787, and 209,282)