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Table 3 KL-divergence result for the mosaic image created using multiple MBIs

From: Robust normalization protocols for multiplexed fluorescence bioimage analysis

 

k-means

AGHC

 

CC

NN

CN

CC

NN

CN

R

0.43

0.51

5.97

0.13

0.32

0.56

I

0.26

0.22

8.37

0.25

0.27

0.58

II

0.16

0.48

0.42

0.13

0.15

0.14

III

0.52

0.19

2.08

0.09

0.12

0.22

IV

0.16

0.42

0.46

0.10

0.14

0.21

V

0.46

0.33

10.08

0.25

0.27

0.21

VI

0.26

0.35

0.36

0.13

0.13

0.13

VII

0.52

0.16

1.22

0.07

0.14

0.13

VIII

0.22

0.43

0.66

0.08

0.16

0.13

  1. CC represents cancer vs cancer, NN represents normal vs normal and CN represents Cancer vs Normal KL-divergence. Protocol I (bold) produces high inter-class divergence while simultaneously preserving low intra-class divergence