Fig. 2
From: Iteratively refining breast cancer intrinsic subtypes in the METABRIC dataset
The heat map of refined intrinsic features selected using CM1 score in the refinement process. The heat map diagram exhibit 35 probes (rows) and 1992 samples (columns) from the discovery and validation sets ordered according to gene expression similarity. For visualisation, the expression values are normalised across the probes using a two-sided threshold of 1 % (for under- and over-expression). The bars on the bottom show the sample distribution according to the refined and original labels assigned to the METABRIC cohort. The subtypes are defined as follow: luminal A (blue), luminal B (green), HER2-enriched (yellow), normal-like (purple), basal-like (red), and inconsistent (grey)