Table 5 List of genes with at least 15 connections (i.e., hubs*) in the networks, ranked by the number of connections for each gene

IL6

70

TP53

42

TNF

69

BCL2**

28

CXCL8

56

MYC

16

IL1B

55

PARP1

16

ERK1/2

54

P38 MAPK

15

VEGFA

52

TNF

15

MAPK1

51

NFkB (complex)

46

P38 MAPK

45

TGFB1

43

COL18A1

42

CCL2

39

IFNG

38

PTGS2

37

ERK

34

TP53

34

MAPK3

33

Akt

32

STAT3

30

CD3

29

JUN

29

PI3K (complex)

29

EGFR

28

MMP1

28

HGF

27

Jnk

27

CCL5

26

CD40

26

IL1A

26

ITGB1**

26

MMP2

25

Cg

24

FN1

24

RELA

24

TLR4

23

Vegf

23

CXCL10

22

EGF

21

ITGB3

21

MAPK14

21

NFKBIA

21

SP1

21

STAT1

21

AKT1

20

HIF1A

20

SRC

20

TERT

20

Pkc(s)

19

CTNNB1

18

Focal adhesion kinase

18

FOS

18

HDAC1

18

IgG

18

ITGAV

18

NFKB1

18

CD44

17

FGF2

17

Lh

17

MAPK8

17

SYK

17

Ap1

16

CCND1

16

IGF1

16

PRKCD

16

TREM1

16

OSM

15