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Table 4 Focus genes* associated with platinum-, taxane-, and platinum/taxane- induced neuropathy, as identified through the literature review

From: Informative gene network for chemotherapy-induced peripheral neuropathy

Platinum-induced neuropathy

Taxane-induced neuropathy

Platinum/Taxane-induced neuropathy

ABCC1

ABCB1

ABCA1

ABCC2

ABCC2

BCL2

ABCG2

ABCG1

CYP2C8

ACYP2

CYP1B1

ERCC1

AGXT

CYP2C8

OPRM1

BTG4

CYP3A4

SOX10

CAMK2N1

CYP3A5

TRPV1

CCNH

EPHA4

 

DLEU7

EPHA5

 

ERCC1

EPHA6

 

FARS2

FANCD2

 

FOXC1

FGD4

 

GMDS

FZD3

 

GSTM1

GSTP1

 

GSTM3

LIMK2

 

GSTP1

SLCO1B1

 

ITGA1

SPIDR

 

ITGB3

TUBB2A

 

KCNN3

XKR4

 

LYRM4

  

PELO

  

POU2AF1

  

SCN10A

  

SCN4A

  

TAC1

  

TSPYL6

  
  1. *Genes shown to be significant based on the literature