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Table 4 Computation times

From: An adaptive permutation approach for genome-wide association study: evaluation and recommendations for use

   

Time

m

α p

b

Standard predicted

Adaptive empirical (SD)

1,000

5e-5

1,999,900

3.1 days

0.042 (0.026) hours

10,000

5e-6

19,999,900

10 months

0.55 (0.29) hours

100,000

5e-7

199,999,900

84 years

6.0 (2.0) hours

1,000,000

5e-8

1,999,999,900

8400 years

1.9 (0.079) days*

  1. *Based on three observations; others based on 100 replicates.
  2. Computation time comparison of standard and adaptive permutation for varying number of SNPs (m) and times of permutation (b) under the null model.