Table 4 Enriched biological pathways assigned to vWF, HA, and AF by PHPN
From: The multiscale backbone of the human phenotype network based on biological pathways
Von Willebrand factor/ | Atrial fibrillation (AF) pathways1 | Hippocampal atrophy (HA)1 | |||
|---|---|---|---|---|---|
factor VIII pathways1 | Â | Â | pathways | ||
[5412] | Arrhythmogenic right ventricular | [1100] | Metabolic pathways | [4360] | Axon guidance |
[4662] | B cell receptor signaling pathway | [670] | One carbon pool by folate | [4623] | Cytosolic DNA-sensing pathway |
[4514] | Cell adhesion molecules (CAMs) | Â | Â | [531] | Glycosaminoglycan degradation |
[4062] | Chemokine signaling pathway | Â | Â | [4142] | Lysosome |
[4664] | Fc epsilon RI signaling pathway | Â | Â | [1100] | Metabolic pathways |
[1100] | Metabolic pathways | Â | Â | [510] | N-Glycan biosynthesis |
[4666] | Fc gamma R-mediated phagocytosis | Â | Â | [4151] | PI3K-Akt signaling pathway |
[4510] | Focal adhesion | Â | Â | [4141] | Protein processing in endoplasmic reticulum |
[4670] | Leukocyte trans endothelial migration | Â | Â | [4530] | Tight junction |
[4650] | Natural killer cell mediated cytotoxicity | Â | Â | Â | Â |
[4810] | Regulation of actin cytoskeleton | Â | Â | Â | Â |
[4660] | T cell receptor signaling pathway | Â | Â | Â | Â |
[4742] | Taste transduction | Â | Â | Â | Â |