ATIC rs4673990+ MTHFD2 rs12196
|
3.9 (1.6–13.1)
|
0.001*
|
0.013*
|
1.9 (1.2-4.1)
|
0.001*
|
0.027*
|
6.1 (1.8-21.1)
|
<.001*
|
0.002*
|
ATIC rs4673990 + MTHFD2 5nt ins/16nt del
|
3.7 (1.5-12.8)
|
0.001*
|
0.013*
|
1.8 (1.1-3.6)
|
0.003*
|
0.032*
|
6.0 (1.6-22.0)
|
<.001*
|
0.002*
|
MTHFD2 rs12196 + GART rs8971
|
2.8 (1.1-8.8)
|
0.013*
|
0.069
|
1.6 (0.9-3.4)
|
0.016*
|
0.050
|
5.5 (1.3-20.7)
|
0.001*
|
0.009*
|
MTHFD2 5nt ins/16nt del + GART rs8971
|
2.6 (1.0-7.9)
|
0.017*
|
0.069
|
1.5 (0.9-2.7)
|
0.017*
|
0.050
|
5.0 (1.1-20.6)
|
0.002*
|
0.011*
|
ATIC rs4673990 + GART rs8971
|
2.5 (1.1-8.8)
|
0.027*
|
0.071
|
1.4 (0.9-2.4)
|
0.038*
|
0.088
|
4.7 (1.1-19.2)
|
0.009*
|
0.019*
|
ATIC rs2372536 + MTHFD2 5nt ins/16nt del
|
2.5 (1.0-8.3)
|
0.017*
|
0.069
|
1.6 (1.0-3.6)
|
0.006*
|
0.041*
|
5.0 (1.1-17.6)
|
0.011*
|
0.020*
|
ATIC rs2372536 + MTHFD2 rs12196
|
2.4 (0.9-8.0)
|
0.021*
|
0.069
|
1.4 (1.0-3.0)
|
0.033*
|
0.088
|
5.6 (1.2-18.3)
|
0.008*
|
0.019*
|
ATIC rs2372536 + GART rs8971
|
2.2 (0.8-6.5)
|
0.032*
|
0.074
|
1.5 (0.9-2.8)
|
0.015*
|
0.050
|
4.5 (0.8-28.2)
|
0.012*
|
0.020*
|
SLC25A32 rs17803441 +ITPA rs2295553
|
2.4 (0.8-7.5)
|
0.023*
|
0.069
|
1.6 (1.0-2.8)
|
0.013*
|
0.050
|
4.2 (0.8-17.9)
|
0.005*
|
0.019*
|
ATIC rs4673990 + SLC25A32 rs17803441
|
2.3 (0.8-8.2)
|
0.039*
|
0.081
|
1.4 (0.8-2.2)
|
0.061
|
0.106
|
4.9 (0.9-30.9)
|
0.009*
|
0.019*
|
MTHFD2 rs12196 + ITPA rs2295553
|
2.1 (0.9-7.1)
|
0.047*
|
0.090
|
1.4 (0.8-2.1)
|
0.065
|
0.106
|
4.2 (1.0-16.0)
|
0.025*
|
0.034*
|
ATIC rs4673990 + ITPA rs2295553
|
2.3 (0.7-7.1)
|
0.074
|
0.101
|
1.4 (0.7-2.2)
|
0.076
|
0.106
|
3.7 (0.9-13.2)
|
0.045*
|
0.059
|
MTHFD2 rs12196 + SLC25A32 rs17803441
|
2.2 (0.7-6.9)
|
0.060
|
0.097
|
1.4 (0.8-2.3)
|
0.067
|
0.106
|
5.2 (0.9-27.2)
|
0.012*
|
0.020*
|
ATIC rs2372536 + SLC25A32 rs17803441
|
2.2 (0.7-6.1)
|
0.056
|
0.097
|
1.3 (0.9-2.7)
|
0.062
|
0.106
|
6.6 (0.9-37.9)
|
0.008*
|
0.019*
|
MTHFD2 5nt ins/16nt del + MTHFD2 rs12196
|
2.0 (0.9-7.0)
|
0.074
|
0.101
|
1.3 (0.9-2.2)
|
0.088
|
0.115
|
5.2 (0.8-33.1)
|
0.008*
|
0.019*
|
MTHFD2 5nt ins/16nt del +LC25A32 rs17803441
|
2.0 (0.6-5.9)
|
0.077
|
0.101
|
1.3 (0.9-3.3)
|
0.073
|
0.106
|
4.2 (0.7-25.5)
|
0.015*
|
0.023*
|
MTHFD2 5nt ins/16nt del + ITPA rs2295553
|
1.9 (0.8-6.4)
|
0.114
|
0.139
|
1.3 (0.9-2.6)
|
0.129
|
0.160
|
3.9 (0.8-14.6)
|
0.076
|
0.094
|
ATIC rs2372536 + ITPA rs2295553
|
1.9 (0.8-6.9)
|
0.119
|
0.139
|
1.3 (0.9-2.2)
|
0.182
|
0.201
|
3.9 (0.8-13.3)
|
0.091
|
0.101
|
GART rs8971 + ITPA rs2295553
|
1.9 (0.8-8.9)
|
0.186
|
0.195
|
1.3 (0.9-3.6)
|
0.217
|
0.228
|
4.7 (0.8-16.1)
|
0.124
|
0.130
|
ATIC rs2372536 + ATIC rs4673990
|
1.8 (0.7-5.3)
|
0.131
|
0.145
|
1.2 (0.8-2.0)
|
0.161
|
0.188
|
4.0 (0.7-23.3)
|
0.089
|
0.101
|
GART rs8971 + SLC25A32 rs17803441
|
1.7 (0.4-9.9)
|
0.227
|
0.227
|
1.2 (0.7-5.7)
|
0.296
|
0.296
|
3.5 (0.4-19.1)
|
0.156
|
0.156
|