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Table 2 Simulated gene-gene interaction models with varying penetrance functions and minor allele frequencies

From: Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction

   Model 1    Model 2   
  BB Bb bb   BB Bb bb
AA 0 0.1 0 AA 0 0 0.1
Aa 0.1 0 0.1 Aa 0 0.05 0
aa 0 0.1 0 aa 0.1 0 0
   (A) MAF=0.5     (B) MAF=0.5  
   Model 3     Model 4  
  BB Bb bb   BB Bb bb
AA 0.08 0.07 0.05 AA 0.09 0.05 0.02
Aa 0.1 0 0.1 Aa 0.08 0.09 0.01
aa 0.03 0.1 0.04 aa 0.03 0.01 0.03
   (C) MAF=0.25     (D) MAF=0.25