Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction

Table 1 2x2 Predisposing risk table (Subscript i is omitted for n ’s.)

	Case	Control	Total
High Predisposing Risk	$n_{11} = \sum_{j = 1}^{3^{k}} X_{ij} I \{\frac{X_{ij}}{X_{ij} + Y_{ij}} > p_{i 0}\}$	$n_{12} = \sum_{j = 1}^{3^{k}} Y_{ij} I \{\frac{X_{ij}}{X_{ij} + Y_{ij}} > p_{i 0}\}$	n ₁₊
Low Predisposing Risk	$n_{21} = \sum_{j = 1}^{3^{k}} X_{ij} I \{\frac{X_{ij}}{X_{ij} + Y_{ij}} \leq p_{i 0}\}$	$n_{22} = \sum_{j = 1}^{3^{k}} Y_{ij} I \{\frac{X_{ij}}{X_{ij} + Y_{ij}} \leq p_{i 0}\}$	n ₂₊
Total	n ₊₁	n ₊₂	N

ISSN: 1756-0381