Figure 4
From: DA DA: Degree-Aware Algorithms for Network-Based Disease Gene Prioritization
Statistical adjustment based on candidate degree. First, the association score of a candidate with respect to the original seed set is computed. Next, association scores of a large number of randomly selected proteins with similar degree to the candidate are computed using the original seed set. Adjusted score of the candidate protein is then calculated as the statistical significance of the original association score, using this random population of association scores.