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  1. Content type: Research

    Influx of newly determined crystal structures into primary structural databases is increasing at a rapid pace. This leads to updation of primary and their dependent secondary databases which makes large scale ...

    Authors: Eshita Mutt, Sudha Sane Rani and Ramanathan Sowdhamini

    Citation: BioData Mining 2013 6:20

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  2. Content type: Review

    Currently there are definitions from many agencies and research societies defining “bioinformatics” as deriving knowledge from computational analysis of large volumes of biological and biomedical data. Should thi...

    Authors: Xiuzhen Huang, Barry Bruce, Alison Buchan, Clare Bates Congdon, Carole L Cramer, Steven F Jennings, Hongmei Jiang, Zenglu Li, Gail McClure, Rick McMullen, Jason H Moore, Bindu Nanduri, Joan Peckham, Andy Perkins, Shawn W Polson, Bhanu Rekepalli…

    Citation: BioData Mining 2013 6:19

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  3. Content type: Software article

    With the abundance of information and analysis results being collected for genetic loci, user-friendly and flexible data visualization approaches can inform and improve the analysis and dissemination of these ...

    Authors: Daniel Wolfe, Scott Dudek, Marylyn D Ritchie and Sarah A Pendergrass

    Citation: BioData Mining 2013 6:18

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  4. Content type: Research

    Over-sampling methods based on Synthetic Minority Over-sampling Technique (SMOTE) have been proposed for classification problems of imbalanced biomedical data. However, the existing over-sampling methods achie...

    Authors: Munehiro Nakamura, Yusuke Kajiwara, Atsushi Otsuka and Haruhiko Kimura

    Citation: BioData Mining 2013 6:16

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  5. Content type: Review

    Elucidating the content of a DNA sequence is critical to deeper understand and decode the genetic information for any biological system. As next generation sequencing (NGS) techniques have become cheaper and m...

    Authors: Georgios A Pavlopoulos, Anastasis Oulas, Ernesto Iacucci, Alejandro Sifrim, Yves Moreau, Reinhard Schneider, Jan Aerts and Ioannis Iliopoulos

    Citation: BioData Mining 2013 6:13

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  6. Content type: Research

    Public domain databases nowadays provide multiple layers of genome-wide data e.g., promoter methylation, mRNA expression, and miRNA expression and should enable integrative modeling of the mechanisms of regula...

    Authors: Y-h Taguchi

    Citation: BioData Mining 2013 6:11

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  7. Content type: Methodology

    Applying a statistical method implies identifying underlying (model) assumptions and checking their validity in the particular context. One of these contexts is association modeling for epistasis detection. He...

    Authors: Jestinah M Mahachie John, François Van Lishout, Elena S Gusareva and Kristel Van Steen

    Citation: BioData Mining 2013 6:9

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  8. Content type: Short report

    Identifying high-order genetics associations with non-additive (i.e. epistatic) effects in population-based studies of common human diseases is a computational challenge. Multifactor dimensionality reduction (...

    Authors: Ryan L Collins, Ting Hu, Christian Wejse, Giorgio Sirugo, Scott M Williams and Jason H Moore

    Citation: BioData Mining 2013 6:4

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  9. Content type: Short report

    Decades after the eradication of smallpox, its etiological agent, variola virus (VARV), remains a threat as a potential bioweapon. Outbreaks of smallpox around the time of the global eradication effort exhibit...

    Authors: Anne Gatewood Hoen, Shea N Gardner and Jason H Moore

    Citation: BioData Mining 2013 6:3

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  10. Content type: Research

    Glucocorticoids are potent anti-inflammatory agents used for the treatment of diseases such as rheumatoid arthritis, asthma, inflammatory bowel disease and psoriasis. Unfortunately, usage is limited because of...

    Authors: Wilco WM Fleuren, Erik JM Toonen, Stefan Verhoeven, Raoul Frijters, Tim Hulsen, Ton Rullmann, René van Schaik, Jacob de Vlieg and Wynand Alkema

    Citation: BioData Mining 2013 6:2

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  11. Content type: Methodology

    Multifactor Dimensionality Reduction (MDR) has been widely applied to detect gene-gene (GxG) interactions associated with complex diseases. Existing MDR methods summarize disease risk by a dichotomous predispo...

    Authors: Hongying Dai, Richard J Charnigo, Mara L Becker, J Steven Leeder and Alison A Motsinger-Reif

    Citation: BioData Mining 2013 6:1

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  12. Content type: Short report

    The large sample sizes, freedom of ethical restrictions and ease of repeated measurements make cytotoxicity assays of immortalized lymphoblastoid cell lines a powerful new in vitro method in pharmacogenomics rese...

    Authors: Chad C Brown, Tammy M Havener, Marisa Wong Medina, Ronald M Krauss, Howard L McLeod and Alison A Motsinger‐Reif

    Citation: BioData Mining 2012 5:21

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  13. Content type: Methodology

    Each omics platform is now able to generate a large amount of data. Genomics, proteomics, metabolomics, interactomics are compiled at an ever increasing pace and now form a core part of the fundamental systems...

    Authors: Ignacio González, Kim-Anh Lê Cao, Melissa J Davis and Sébastien Déjean

    Citation: BioData Mining 2012 5:19

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Page 8 of 11

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