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Table 2 Feature selection of stepwise logistic regression model

From: Interpretable recurrent neural network models for dynamic prediction of the extubation failure risk in patients with invasive mechanical ventilation in the intensive care unit

Features

OR [95% CI]

P value

Demographic characteristics

 Weight (with each 10 kg increment)

0.971 [0.947, 0.995]

0.017

 Admission type (unscheduled surgical as reference)

  Medical

1.195 [1.054, 1.356]

0.005

  Scheduled surgical

0.696 [0.492, 0.986]

0.041

Comorbidities

  

 Cerebrovascular disease

1.395 [1.198, 1.626]

 < 0.001

 Paraplegia

1.685 [1.340, 2.118]

 < 0.001

 Metastatic solid tumor

1.587 [1.241, 2.029]

 < 0.001

Vital signs

 HR (with every 10 beats/min increment)

1.047 [1.014, 1.082]

0.005

 RR

1.019 [1.007, 1.031]

0.001

 SpO2

0.943 [0.921, 0.964]

 < 0.001

GCS

 GCS eyes

0.773 [0.723, 0.826]

 < 0.001

 GCS motor

0.844 [0.811, 0.879]

 < 0.001

Blood biochemistry

 PaCO2 (with every 10 mmHg increment)

1.151 [1.076, 1.231]

 < 0.001

 Glucose

1.002 [1.001, 1.004]

 < 0.001

 Hemoglobin

0.910 [0.880, 0.940]

 < 0.001

 BUN

1.008 [1.005, 1.012]

 < 0.001

 Creatinine (with every 0.1 mg/dl increment)

0.986 [0.979, 0.994]

 < 0.001

 Sodium (with every 10 mmol/L increment)

1.397 [1.275, 1.532]

 < 0.001

 Calcium

0.883 [0.813, 0.959]

0.003

 Anion gap

1.061 [1.042, 1.081]

 < 0.001

 PTT

1.005 [1.002, 1.008]

0.002

 INR

1.182 [1.064, 1.314]

0.002

Ventilator parameters

 Ppeak

1.037 [1.027, 1.047]

 < 0.001

 PEEP

1.082 [1.057, 1.107]

 < 0.001

 Inspiratory flow rate

1.011 [1.008, 1.013]

 < 0.001

Norepinephrine (with every 0.1 mcg/kg/min increment)

1.308 [1.228, 1.394]

 < 0.001

Intravenous antibiotics

0.843 [0.743, 0.957]

0.008

CRRT

1.734 [1.319, 2.280]

 < 0.001

  1. Abbreviations: CI confidence interval, CRRT continuous renal replacement therapy, GCS Glasgow Coma Scale, HR heart rate, INR international normalized ratio, OR odds ratio, PEEP positive end expiratory pressure, Ppeak peak inspiratory pressure, PTT partial thromboplastin time, RR respiratory rate