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Table 1 Baseline static features between the successful and failed extubation group

From: Interpretable recurrent neural network models for dynamic prediction of the extubation failure risk in patients with invasive mechanical ventilation in the intensive care unit

 

IMV patients (n = 8599)

Training set (n = 6879)

P value

Test set (n = 1720)

P value

Successful extubation (n = 4790)

Failed extubation (n = 2089)

Successful extubation (n = 1200)

Failed extubation (n = 520)

Gender (male), n (%)

2862 (59.7)

1228 (58.8)

0.470

680 (56.7)

292 (56.2)

0.885

Age (y, mean (SD))

63.07 (16.11)

63.18 (15.86)

0.811

63.69 (15.88)

64.29 (15.19)

0.464

BMI (kg/m2, mean (SD))

29.34 (7.52)

29.97 (8.60)

0.006

29.02 (7.62)

30.19 (9.22)

0.015

Admission type

  

 < 0.001

  

 < 0.001

 Medical, n (%)

2927 (61.1)

1534 (73.4)

 

725 (60.4)

383 (73.6)

 

 Unscheduled surgical, n (%)

1619 (33.8)

511 (24.5)

 

414 (34.5)

131 (25.2)

 

 Scheduled surgical, n (%)

244 (5.1)

44 (2.1)

 

61 (5.1)

6 (1.2)

 

Comorbidities

 Myocardial infarction, n (%)

932 (19.5)

397 (19.0)

0.686

234 (19.5)

94 (18.1)

0.533

 Congestive heart failure, n (%)

1319 (27.5)

596 (28.5)

0.414

370 (30.8)

155 (29.8)

0.713

 Chronic pulmonary disease, n (%)

1250 (26.1)

577 (27.6)

0.198

331 (27.6)

137 (26.3)

0.638

 Peptic ulcer disease, n (%)

151 (3.2)

64 (3.1)

0.905

37 (3.1)

19 (3.7)

0.642

 Liver disease, n (%)

671 (14.0)

453 (21.7)

 < 0.001

157 (13.1)

111 (21.3)

 < 0.001

 Renal disease, n (%)

884 (18.5)

406 (19.4)

0.355

239 (19.9)

101 (19.4)

0.865

 Peripheral vascular disease, n (%)

685 (14.3)

284 (13.6)

0.462

156 (13.0)

66 (12.7)

0.923

 Cerebrovascular disease, n (%)

725 (15.1)

428 (20.5)

 < 0.001

183 (15.2)

118 (22.7)

 < 0.001

 Paraplegia, n (%)

238 (5.0)

155 (7.4)

 < 0.001

51 (4.3)

37 (7.1)

0.018

 Diabetes, n (%)

1367 (28.5)

594 (28.4)

0.953

358 (29.8)

162 (31.2)

0.624

 Malignant cancer, n (%)

513 (10.7)

300 (14.4)

 < 0.001

135 (11.3)

55 (10.6)

0.745

 Metastatic solid tumor, n (%)

206 (4.3)

147 (7.0)

 < 0.001

52 (4.3)

23 (4.4)

0.964

 AIDS, n (%)

27 (0.6)

16 (0.8)

0.417

5 (0.4)

3 (0.6)

0.950

Ventilation time (hours, median [IQR])

25.0 [17.0, 54.1]

47.0 [24.0, 103.0]

 < 0.001

24.0 [17.2, 48.0]

47.7 [26.0, 103.0]

 < 0.001