| IMV patients (n = 8599) | |||||
---|---|---|---|---|---|---|
Training set (n = 6879) | P value | Test set (n = 1720) | P value | |||
Successful extubation (n = 4790) | Failed extubation (n = 2089) | Successful extubation (n = 1200) | Failed extubation (n = 520) | |||
Gender (male), n (%) | 2862 (59.7) | 1228 (58.8) | 0.470 | 680 (56.7) | 292 (56.2) | 0.885 |
Age (y, mean (SD)) | 63.07 (16.11) | 63.18 (15.86) | 0.811 | 63.69 (15.88) | 64.29 (15.19) | 0.464 |
BMI (kg/m2, mean (SD)) | 29.34 (7.52) | 29.97 (8.60) | 0.006 | 29.02 (7.62) | 30.19 (9.22) | 0.015 |
Admission type |  |  |  < 0.001 |  |  |  < 0.001 |
 Medical, n (%) | 2927 (61.1) | 1534 (73.4) |  | 725 (60.4) | 383 (73.6) |  |
 Unscheduled surgical, n (%) | 1619 (33.8) | 511 (24.5) |  | 414 (34.5) | 131 (25.2) |  |
 Scheduled surgical, n (%) | 244 (5.1) | 44 (2.1) |  | 61 (5.1) | 6 (1.2) |  |
Comorbidities | ||||||
 Myocardial infarction, n (%) | 932 (19.5) | 397 (19.0) | 0.686 | 234 (19.5) | 94 (18.1) | 0.533 |
 Congestive heart failure, n (%) | 1319 (27.5) | 596 (28.5) | 0.414 | 370 (30.8) | 155 (29.8) | 0.713 |
 Chronic pulmonary disease, n (%) | 1250 (26.1) | 577 (27.6) | 0.198 | 331 (27.6) | 137 (26.3) | 0.638 |
 Peptic ulcer disease, n (%) | 151 (3.2) | 64 (3.1) | 0.905 | 37 (3.1) | 19 (3.7) | 0.642 |
 Liver disease, n (%) | 671 (14.0) | 453 (21.7) |  < 0.001 | 157 (13.1) | 111 (21.3) |  < 0.001 |
 Renal disease, n (%) | 884 (18.5) | 406 (19.4) | 0.355 | 239 (19.9) | 101 (19.4) | 0.865 |
 Peripheral vascular disease, n (%) | 685 (14.3) | 284 (13.6) | 0.462 | 156 (13.0) | 66 (12.7) | 0.923 |
 Cerebrovascular disease, n (%) | 725 (15.1) | 428 (20.5) |  < 0.001 | 183 (15.2) | 118 (22.7) |  < 0.001 |
 Paraplegia, n (%) | 238 (5.0) | 155 (7.4) |  < 0.001 | 51 (4.3) | 37 (7.1) | 0.018 |
 Diabetes, n (%) | 1367 (28.5) | 594 (28.4) | 0.953 | 358 (29.8) | 162 (31.2) | 0.624 |
 Malignant cancer, n (%) | 513 (10.7) | 300 (14.4) |  < 0.001 | 135 (11.3) | 55 (10.6) | 0.745 |
 Metastatic solid tumor, n (%) | 206 (4.3) | 147 (7.0) |  < 0.001 | 52 (4.3) | 23 (4.4) | 0.964 |
 AIDS, n (%) | 27 (0.6) | 16 (0.8) | 0.417 | 5 (0.4) | 3 (0.6) | 0.950 |
Ventilation time (hours, median [IQR]) | 25.0 [17.0, 54.1] | 47.0 [24.0, 103.0] |  < 0.001 | 24.0 [17.2, 48.0] | 47.7 [26.0, 103.0] |  < 0.001 |