Fig. 1

Manhattan plot of the differences in SNPs between patients with RA and SLE. A whole genome and (B) detailed HLA region. Blue- and red-dotted lines indicate thresholds for significance (p < 1 × 10⁻⁵ and p < 5 × 10⁻⁸, respectively). Xaxis: chromosome number; yaxis: log₁₀^P; SNP: single nucleotide polymorphism; RA: rheumatoid arthritis; SLE: systemic lupus erythematosus