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Table 3 Variable selection of stepwise logistic regression model

From: Development and validation of a novel blending machine learning model for hospital mortality prediction in ICU patients with Sepsis

Variables

OR [95% CI]

P-value

Demographic characteristics

 BMI

0.986 [0.979, 0.993]

< 0.001

 Age (with each 10 years increment)

1.269 [1.219, 1.322]

< 0.001

Admission type (unscheduled surgery as reference)

 Internal medicine

1.526 [1.185, 1.964]

0.001

 Scheduled surgery

0.936 [0.504, 1.738]

0.834

Comorbidities

 AIDS

2.281 [1.343, 3.873]

0.002

 Hematological tumor

2.279 [1.661, 3.126]

< 0.001

 Metastatic cancer

2.593 [1.858, 3.618]

< 0.001

Vital signs

 Minimum HR (with every 10 beats/min increment)

1.110 [1.073, 1.147]

< 0.001

 Maximum RR

1.016 [1.009, 1.022]

< 0.001

 Minimum RR

1.022 [1.012, 1.033]

< 0.001

 Minimum temperature

0.811 [0.766, 0.858]

< 0.001

 Minimum SBP (with every 10 mmHg increment)

0.922 [0.880, 0.966]

0.001

 Minimum MAP (with every 10 mmHg increment)

0.927 [0.872,0.986]

0.016

 Minimum SpO2

0.981 [0.976, 0.986]

< 0.001

Laboratory tests

 Minimum PaO2 (with every 10 mmHg increment)

1.020 [1.005, 1.035]

0.010

 Maximum PaCO2 (with every 10 mmHg increment)

1.075 [1.041, 1.109]

< 0.001

 Minimum PaO2/FiO2 (with every 20 mmHg increment)

0.940 [0.926, 0.955]

< 0.001

 Maximum WBC

0.989 [0.979, 0.998]

0.023

 Minimum WBC

1.021 [1.009, 1.034]

0.001

 Minimum platelet (with every 20*1012/L increment)

0.981 [0.971, 0.992]

0.001

 Maximum hemoglobin

0.942 [0.918, 0.966]

< 0.001

 Minimum bilirubin

1.073 [1.048, 1.098]

< 0.001

 Maximum albumin

0.679 [0.578, 0.799]

< 0.001

 Minimum albumin

0.848 [0.720, 0.999]

0.049

 Maximum creatinine (with every 0.1 mg/dl increment)

0.991 [0.987, 0.996]

< 0.001

 Minimum BUN

1.009 [1.006, 1.012]

< 0.001

 Minimum sodium (with every 10 mmol/L increment)

0.900 [0.830, 0.975]

0.010

 Minimum potassium

1.110 [1.018, 1.211]

0.019

 Maximum lactate

1.072 [1.043, 1.102]

< 0.001

 Minimum lactate

1.120 [1.067, 1.176]

< 0.001

 Maximum PT

1.013 [1.006, 1.020]

< 0.001

Minimum GCS

0.943 [0.927, 0.960]

< 0.001

Mechanical ventilation

1.687 [1.506, 1.891]

< 0.001

Renal replacement therapy

1.730 [1.274, 2.349]

0.037

24 h urine output (with every 200 ml increment)

0.973 [0.963, 0.983]

< 0.001

  1. Abbreviations: OR odds ratio, CI confidence interval, BMI body mass index, HR heart rate, RR respiratory rate, SBP systolic blood pressure, MAP mean arterial pressure, GCS Glasgow Coma Scale, WBC white blood cell count, PT prothrombin time
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ISSN: 1756-0381