Fig. 3
From: Comparison of 16S and whole genome dog microbiomes using machine learning
A. The phylogenetic tree generated by RAxML (Randomized Axelerated Maximum Likelihood) of B. coprocola genomes present in all WGS samples. The reference genome (GCF_000154845.1) is shown in pink. Strains between samples labelled by phenotype (baseline diet (BASE), high protein, low carbohydrate (HPLC) and low protein, high carbohydrate (LPHC) with overweight (OW) and lean (LN) phenotypes) show minimal preferential clustering. B. The corresponding multiple sequence alignment represents the leuB gene sequence for each member of the phylogenetic tree. The sequence is largely conserved across all clusters with the exception of SNPs at positions 28028 and 28033, suggesting the increase in leuB relative abundance in HPLC diets is driven by the abundance of B. Coprocola