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Fig. 3 | BioData Mining

Fig. 3

From: Personalized single-cell networks: a framework to predict the response of any gene to any drug for any patient

Fig. 3

A bird’s-eye view of the data collection, integration, and analysis steps performed in this study. We use RWR to combine general knowledge with some specific knowledge about a sample. We separately use gene function and drug-response data as the source of general knowledge. We use co-expression networks as the source of specific knowledge. By combining the drug-response data with an individualized single-cell network, we can make predictions about gene behavior that are personalized to each patient. Concept nodes are colored by activity type: data processing (gray), validation of gene-annotation prediction (green), validation of gene-drug prediction (yellow), and exploratory application (orange)

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