Fig. 1

This figure shows a histogram of chromosome scale length variation for most of chromosomes 1,6,13, and 17. For most patients in the TCGA dataset, a normal blood sample was taken, genomic DNA was extracted from that sample and analyzed with an Affymetrix SNP 6.0 array. The data from this array was processed by the TCGA project through a bioinformatic pipeline that resulted in a segment mean value, which is a number equal to the log base two of one half the copy number value. This histogram indicates that most people have a nominal value of 0, indicating exactly two copies of the diploid chromosome. A value of 0.02 would indicate the person has on average 2.028 copies of the chromosome, or about 1.4% longer than the average length of the chromosome