Fig. 3

a Heatmap of 5’ breakpoint vs 3’ breakpoints from long-read TRS-independent discontinuous transcripts. Reads were considered TRS-independent discontinuous transcripts if the leader sequence was not near the transcription regulatory sequence and the aligned read contained a deletion of 100 or more bases. The heatmap and histograms are in bins of 100 bases. Colors in the heatmap and amplitude of blue and green lines are log-normalized. b The log-normalized number of discontinuous transcripts with given 5’ and 3’ breakpoints overlaid with the locations of the indels (by 5’ start position)