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Table 2 Estimates of Type I error for MBMDR-PC, MBMDR-GC, and MDR-SP, with a nominal 0.05 FWER level

From: Performance of model-based multifactor dimensionality reduction methods for epistasis detection by controlling population structure

  b = 40%
Method Sample sizes Markers d = 0.1 d = 0.3
MBMDR-PC 200 200 0.050 0.046
   400 0.051 0.051
   800 0.046 0.048
  300 200 0.046 0.047
   400 0.047 0.049
   800 0.049 0.047
  400 200 0.050 0.053
   400 0.051 0.054
   800 0.048 0.046
MDR-SP 200 200 0.054 0.054
   400 0.062 0.055
   800 0.062 0.050
  300 200 0.051 0.056
   400 0.055 0.051
   800 0.044 0.046
  400 200 0.044 0.050
   400 0.046 0.052
   800 0.044 0.065
MBMDR-GC 200 200 0.059 0.058
   400 0.061 0.065
   800 0.064 0.067
  300 200 0.060 0.065
   400 0.062 0.071
   800 0.063 0.068
  400 200 0.066 0.069
   400 0.061 0.071
   800 0.063 0.066
  1. Note: d denotes the difference of candidate allele frequencies in the two subpopulations, and b denotes the percentage of cases from the European subpopulation
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