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Table 6 NPV, PPV, SEN, SPE and AUC values for each of US characteristic in overall nodules

From: Diagnosis of thyroid nodules for ultrasonographic characteristics indicative of malignancy using random forest

Characteristic Benign Malignant NPV PPV SEN SPE AUC
Shape        
AP/T≥1 89 685 32.9% 88.5% 56.6% 74.4% 0.655
AP/T<1 258 526    Reference   
Margin        
Regular 180 189    Reference   
Irregular 167 1022 48.8% 86.0% 84.4% 51.9% 0.681
Border        
Unclear 137 820 34.9% 85.7% 67.7% 60.5% 0.641
Clear 210 391    Reference   
Hackly border        
Present 91 745 35.5% 89.1% 61.5% 73.8% 0.676
Absent 256 466    Reference   
Component        
Solid 207 1158 72.5% 84.8% 95.6% 40.3% 0.680
Mixed 140 53    Reference   
Calcifications        
Macro-calcifications 46 137 21.9% 74.9% 11.3% 86.7% 0.490
Micro-calcifications 139 712 29.4% 83.7% 58.8% 59.9% 0.594
No calcifications 162 362    Reference   
Halo        
Present 303 1132 35.8% 78.9% 93.5% 12.7% 0.531
Absent 44 79    Reference   
Attenuation        
Present 33 208 23.8% 86.3% 17.2% 90.5% 0.538
Absent 314 1003    Reference   
Lateral shadow        
Present 9 52 22.6% 85.2% 4.3% 97.4% 0.509
Absent 338 1159    Reference   
Blood flow degree        
Low 80 417 25.2% 83.9% 34.4% 76.9% 0.557
Medium 152 402    Reference   
High 115 392 22.1% 77.3% 32.4% 66.9% 0.496
Vascularity        
Peripheral 103 255    Reference   
Mixed 88 231 20.9% 72.4% 19.1% 74.6% 0.469
Central 156 725 28.2% 82.3% 59.9% 55.0% 0.575
Echogenicity        
Hypoechoic 198 925 34.3% 82.4% 76.4% 42.9% 0.597
Hyperechoic 149 286    Reference   
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