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Table 6 NPV, PPV, SEN, SPE and AUC values for each of US characteristic in overall nodules

From: Diagnosis of thyroid nodules for ultrasonographic characteristics indicative of malignancy using random forest

Characteristic

Benign

Malignant

NPV

PPV

SEN

SPE

AUC

Shape

       

AP/T≥1

89

685

32.9%

88.5%

56.6%

74.4%

0.655

AP/T<1

258

526

  

Reference

  

Margin

       

Regular

180

189

  

Reference

  

Irregular

167

1022

48.8%

86.0%

84.4%

51.9%

0.681

Border

       

Unclear

137

820

34.9%

85.7%

67.7%

60.5%

0.641

Clear

210

391

  

Reference

  

Hackly border

       

Present

91

745

35.5%

89.1%

61.5%

73.8%

0.676

Absent

256

466

  

Reference

  

Component

       

Solid

207

1158

72.5%

84.8%

95.6%

40.3%

0.680

Mixed

140

53

  

Reference

  

Calcifications

       

Macro-calcifications

46

137

21.9%

74.9%

11.3%

86.7%

0.490

Micro-calcifications

139

712

29.4%

83.7%

58.8%

59.9%

0.594

No calcifications

162

362

  

Reference

  

Halo

       

Present

303

1132

35.8%

78.9%

93.5%

12.7%

0.531

Absent

44

79

  

Reference

  

Attenuation

       

Present

33

208

23.8%

86.3%

17.2%

90.5%

0.538

Absent

314

1003

  

Reference

  

Lateral shadow

       

Present

9

52

22.6%

85.2%

4.3%

97.4%

0.509

Absent

338

1159

  

Reference

  

Blood flow degree

       

Low

80

417

25.2%

83.9%

34.4%

76.9%

0.557

Medium

152

402

  

Reference

  

High

115

392

22.1%

77.3%

32.4%

66.9%

0.496

Vascularity

       

Peripheral

103

255

  

Reference

  

Mixed

88

231

20.9%

72.4%

19.1%

74.6%

0.469

Central

156

725

28.2%

82.3%

59.9%

55.0%

0.575

Echogenicity

       

Hypoechoic

198

925

34.3%

82.4%

76.4%

42.9%

0.597

Hyperechoic

149

286

  

Reference

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