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Table 2 NPV, PPV, SEN, SPE and AUC values for each of US characteristic in disease nodules

From: Diagnosis of thyroid nodules for ultrasonographic characteristics indicative of malignancy using random forest

Characteristic

Benign

Malignant

NPV

PPV

SEN

SPE

AUC

Shape

       

AP/T≥1

34(4.7%)

684(95.3%)

29.3%

95.3%

57.0%

86.3%

0.716

AP/T<1

214(29.3%)

516(70.7%)

Reference

    

Margin

       

Regular

174(49.2%)

180(50.8%)

Reference

    

Irregular

74(6.8%)

1020(93.2%)

49.2%

93.2%

85.0%

70.2%

0.776

Border

       

Unclear

55(6.3%)

819(93.7%)

33.6%

93.7%

68.2%

77.8%

0.730

Clear

193(33.6%)

381(66.4%)

Reference

    

Hackly border

       

Present

22(3.0%)

744(97%)

33.1%

97.1%

62.0%

91.1%

0.766

Absent

226 (33.1%)

456(66.9%)

Reference

    

Component

       

Solid

108(8.5%)

1157(91.5%)

76.5%

91.5%

96.4%

56.5%

0.764

Mixed

140(76.5%)

43(23.5%)

Reference

    

Calcifications

       

Macro-calcifications

30(18.0%)

137(82.0%)

17.0%

82.0%

11.4%

87.9%

0.497

Micro-calcifications

78(9.9%)

711(90.1%)

25.8%

90.1%

59.2%

68.5%

0.639

No calcifications

140(28.5%)

352(71.5%)

Reference

    

Halo

       

Present

209(15.7%)

1123(84.3%)

33.6%

84.3%

93.6%

15.7%

0.547

Absent

39(33.6%)

77(66.4%)

Reference

    

Attenuation

       

Present

12(5.5%)

208(94.5%)

19.2%

94.5%

17.3%

95.2%

0.562

Absent

236(19.2%)

992(80.8%)

Reference

    

Lateral shadow

       

Present

5(8.8%)

52(91.2%)

17.5%

91.2%

4.3%

98.0%

0.512

Absent

243(17.5%)

1148(82.5%)

Reference

    

Blood flow degree

       

Low

49(10.5%)

417(89.5%)

20.3%

89.5%

34.8%

80.2%

0.575

Medium

116(22.7%)

396(77.3%)

Reference

    

High

83(17.7%)

387(82.3%)

16.9%

82.3%

32.2%

66.5%

0.494

Vascularity

       

Peripheral

78(23.8%)

250(76.2%)

Reference

    

Mixed

69(23.2%)

228(76.8%)

15.6%

76.8%

19.0%

72.2%

0.456

Central

101(12.3%)

722(87.7%)

23.5%

87.7%

60.2%

59.3%

0.597

Echogenicity

       

Hypoechoic

117(11.3%)

920(88.7%)

31.9%

88.7%

76.7%

52.8%

0.647

Hyperechoic

131(31.9%)

280(68.1%)

Reference

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