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Table 3 Gene candidates with known indications. Results are queried from DrugBank

From: Identification of therapeutic targets from genetic association studies using hierarchical component analysis

Target

Indication

Drug

GWAS components + BNs

 ALOX5

UC

Mesalazine

 SLOC1A2

RA

Hydrocortisone, Ibuprofen, Indomethacin

 FCGR3A

RA

Etanercept

 C1QA

RA

Etanercept

S-PrediXcan

 TNF

UC

Infliximab

 TNF

RA

Chloroquine, Etanercept, Infliximab

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BioData Mining

ISSN: 1756-0381