| |
AMD
|
CD
|
UC
|
RA
|
|---|
|
GWAS components + BNs (p1)
|
|
LINCS hits
|
0.059 (3/51)
|
0.143 (2/14)
|
0.146 (6/41)
|
0.326 (17/52)
|
|
MGI hits
|
0.311 (42/135)
|
0.326 (15/46)
|
0.361 (35/97)
|
0.493 (73/148)
|
|
S-Predixcan (p2)
|
|
LINCS hits
|
0.093 (5/54)
|
0.243 (18/74)
|
0.121 (7/58)
|
0.237 (22/93)
|
|
MGI hits
|
0.227 (29/128)
|
0.367 (50/136)
|
0.269 (28/104)
|
0.277 (57/206)
|
|
p1– p2
|
|
LINCS hits
|
−0.034
|
−0.1
|
0.025
|
0.089
|
|
MGI hits
|
0.084
|
− 0.047
|
0.092
|
0.216***
|
- Numerators represent hits, and denominators represent the number of genes retrieved by GWAS components + BNs or S-PrediXcan. *** indicates p < 0.001
