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Table 1 Gene pairs co-expressed in multiple tissues and genetically conserved gene pairs. P-values report the difference in ratios compared to the one estimated from gene pairs found in one tissue (bottom row)

From: Identification of therapeutic targets from genetic association studies using hierarchical component analysis

# tissues detected

# WGCNA edge (n1)

# genetically conserved edges (n2)

ratio (n2 / n1)

p-value

14

1

0

0

0.548

13

1

1

1

8.78 × 10−23

12

7

2

0.286

3.58 × 10−13

11

9

5

0.556

1.68 × 10−58

10

12

4

0.333

1.75 × 10−28

9

19

8

0.420

2.06 × 10− 69

8

28

15

0.536

6.96 × 10− 163

7

33

14

0.424

6.65 × 10− 120

6

43

14

0.326

3.58 × 10− 91

5

75

20

0.267

4.62 × 10− 104

4

180

45

0.25

1.18 × 10− 209

3

495

87

0.176

2.21 × 10− 261

2

3344

218

0.0652

1.96 × 10− 170

1

78,656

817

0.0104

N/A