Fig. 5
From: The accelerated aging model reveals critical mechanisms of late-onset Parkinson’s disease
The shortest paths for enrichment analysis of KEGG and BP. a The maximum number of enriched paths for KEGG pathway (PPAR signaling pathway, p = 6.0624e-05, FDR = 0.0113; p = 2.0267e-05, FDR = 0.0038; p = 6.0624e-05, FDR = 0.0113); b The most significant BP path (Immunological memory formation process, GO:0090715, p = 8.7146e-07, FDR = 0.0051); c The maximum number of enriched paths for BP pathway (Alpha-Beta T cell differentiation, GO:0046632, p = 1.2141e-04, FDR = 0.0744; p = 4.0638e-05, FDR = 0.0996; p = 4.0638e-05, FDR = 0.0498). The yellow nodes represent the aging biomarkers, the blue nodes represent the genes connecting aging biomarkers and PD biomarkers, the green nodes represent the PD biomarkers, and the genes in the red square frames coincide with those genes in the enriched functions. “PPAR*”: the PPAR signaling pathway