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Table 2 Meaningful mouse genes lost in long-lived mammals

From: Screening for mouse genes lost in mammals with long lifespans

Ensembl ID

Chr.

Gene symbol

Description

Max. expression

 

ENSMUSG00000013353

7

4931406B18Rik

RIKEN cDNA 4931406B18 gene

testis

P

ENSMUSG00000013653

11

1810065E05Rik

RIKEN cDNA 1810065E05 gene

stomach, caecum

–

ENSMUSG00000014529

5

Tmbim7

transmembrane BAX inhibitor motif containing 7

testis

P

ENSMUSG00000020434

11

4921536K21Rik

RIKEN cDNA 4,921,536 K21 gene

testis

F

ENSMUSG00000022818

16

Cyp2ab1

cytochrome P450, family 2, subfamily ab, polypeptide 1

heart, spleen, placenta

P

ENSMUSG00000034359

4

Skint2

selection and upkeep of intraepithelial T cells 2

thymus, skin

–

ENSMUSG00000037145

11

2210407C18Rik

RIKEN cDNA 2210407C18 gene

stomach

–

ENSMUSG00000038057

11

Dbil5

diazepam binding inhibitor-like 5

testis

P

ENSMUSG00000038994

11

Hils1

histone H1-like protein in spermatids 1

testis

P

ENSMUSG00000043727

2

F830045P16Rik

RIKEN cDNA F830045P16 gene

spleen, MPC

P

ENSMUSG00000044937

10

Ttc41

tetratricopeptide repeat domain 41

testis

P

ENSMUSG00000046196

17

Ttc39d

tetratricopeptide repeat domain 39D

testis

P

ENSMUSG00000050425

7

Mrgprb2

MAS-related GPR, member B2

skin, ovary, forelimb

–

ENSMUSG00000050870

7

Mrgprb8

MAS-related GPR, member B8

testis

–

ENSMUSG00000052642

11

4930504O13Rik

RIKEN cDNA 4930504O13 gene

testis

P

ENSMUSG00000055960

4

Skint4

selection and upkeep of intraepithelial T cells 4

skin, testis, thymus, brain

–

ENSMUSG00000056436

2

Cyct

cytochrome c, testis

testis

P

ENSMUSG00000058287

11

Gm12253

predicted gene 12,253

many organs

–

ENSMUSG00000070868

4

Skint3

selection and upkeep of intraepithelial T cells 3

skin, spleen, lung

–

ENSMUSG00000071724

15

Smpd5

sphingomyelin phosphodiesterase 5

testis

P

ENSMUSG00000076934

16

Iglv1

immunoglobulin lambda variable 1

spleen, colon, thymus

P

ENSMUSG00000076940

16

Iglv2

immunoglobulin lambda variable 2

spleen, thymus, colon

P

ENSMUSG00000078722

4

Gm12394

predicted gene 12,394

brain, testis

F

ENSMUSG00000078934

9

9230113P08Rik

RIKEN cDNA 9230113P08 gene

MPC, brain

F

ENSMUSG00000079606

X

Gm595

predicted gene 595

testis

P

ENSMUSG00000089773

4

Skint1

selection and upkeep of intraepithelial T cells 1

skin, whole organism, thymus

P

ENSMUSG00000095779

4

Gm2163

predicted gene 2163

brain, testis

F

  1. Columns, left to right: Ensembl gene ID, chromosome, gene symbol, gene/protein description, and the organ(s) with the highest gene expression(s). The rightmost column employs the following designations: P, the mouse gene has orthologous flanking genes in humans but is specified as a pseudogene in Ensembl; F, the mouse gene has orthologous flanking genes in humans but is not specified in Ensembl; ‘–’, no alignment of the corresponding regions is available in Ensembl. MPC, medial nasal prominence