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Table 3 Multivariate analysis of the Cox proportional hazard regression model of resected T1-3N0 − 2 M0 NSCLC

From: RNSCLC-PRSP software to predict the prognostic risk and survival in patients with resected T1-3N0–2 M0 non-small cell lung cancer

Factors Variates b SE RR 95%CI P
Gender X1 0.379 0.053 1.460 1.317~1.620 < 0.001
Age X2 −0.403 0.054 0.668 0.601~0.743 < 0.001
N stage 0.001
 N0 X50 −0.372 0.195 0.689 0.470~1.010 0.056
 N1 X51 −0.267 0.075 0.766 0.661~0.886 < 0.001
NELNs < 0.001
 6<N ≤ 12 X61 −0.167 0.060 0.846 0.751~0.952 0.006
 N>12 X62 −0.298 0.064 0.742 0.655~0.841 < 0.001
NPLNs 0.003
 1 ≤ N ≤ 3 X71 0.460 0.197 1.583 1.077~2.328 0.019
 N ≥ 4 X72 0.617 0.203 1.854 1.245~2.762 0.002
Surgery type 0.001
 LET X81 −0.344 0.090 0.709 0.595~0.845 < 0.001
 PET X82 −0.245 0.127 0.783 0.611~1.003 0.053
Primary site 0.035
 Others X90 −0.308 0.172 0.735 0.525~1.029 0.073
 UL X91 −0.105 0.053 0.900 0.811~0.999 0.047
 ML X92 −0.243 0.116 0.784 0.625~0.983 0.035
Histological grade < 0.001
 II X101 0.305 0.100 1.356 1.114~1.651 0.002
 III X102 0.508 0.101 1.663 1.364~2.027 < 0.001
 IV X103 0.754 0.167 2.126 1.532~2.950 < 0.001
Histology 0.011
 AC X111 0.143 0.066 1.153 1.013~1.313 0.031
 S X112 0.170 0.073 1.186 1.028~1.368 0.019
 ASC X113 0.434 0.137 1.544 1.181~2.019 0.001
 BAA X114 −0.030 0.160 0.970 0.709~1.328 0.851
Marital status < 0.001
 Others X120 0.016 0.221 1.016 0.659~1.566 0.944
 Single (never married) X121 −0.133 0.098 0.875 0.723~1.060 0.172
 Married X122 −0.327 0.071 0.721 0.628~0.829 < 0.001
 Divorced X123 −0.247 0.094 0.781 0.650~0.938 0.008
Tumor extensiona < 0.001
 T2 Visc PI X131 −0.115 0.087 0.892 0.752~1.056 0.185
 T2 Centr X132 0.025 0.092 1.025 0.856~1.229 0.786
 T3 Inv X133 0.517 0.204 1.678 1.125~2.500 0.011
 T3 Satell X134 0.340 0.095 1.405 1.167~1.692 < 0.001
Tumor sizea < 0.001
 T1b>1–2(1<T ≤ 2) X141 0.025 0.174 1.025 0.729~1.442 0.886
 T1c>2–3(2<T ≤ 3) X142 0.260 0.171 1.297 1.927~1.815 0.129
 T2a>3–4(3<T ≤ 4) X143 0.457 0.174 1.580 1.122~2.223 0.009
 T2b>4–5(4<T ≤ 5) X144 0.419 0.179 1.520 1.069~2.161 0.020
 T3>5–7(5<T ≤ 7) X145 0.407 0.180 1.502 1.055~2.140 0.024
  1. Abbreviations: b Regression coefficient, SE Standard error, RR Relative risk, CI Confidence interval, NELNs Number of examined regional lymph nodes, NPLNs Number of positive regional lymph nodes, LET Lobectomy, PET Pneumonectomy, UL Upper lobe, ML Middle lobe, II Moderately differentiated, III Poorly differentiated, IV Undifferentiated, AC Adenocarcinoma, S Squamous carcinoma, ASC Adenosquamous carcinoma, BAA Bronchioalveolar adenocarcinoma
  2. a According to the eighth edition AJCC/UICC stage classification for NSCLC