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Table 2 Univariate analysis of the Cox proportional hazard regression model of resected T1-3N0 − 2 M0 NSCLC

From: RNSCLC-PRSP software to predict the prognostic risk and survival in patients with resected T1-3N0–2 M0 non-small cell lung cancer

Factors Variates b SE RR 95%CI P
Gender X1 0.363 0.049 1.438 1.307~1.582 < 0.001
Age X2 −0.354 0.050 0.702 0.637~0.774 < 0.001
Laterality X3 − 0.009 0.049 0.991 0.900~1.091 0.858
Race (as dummy variables) X4      
 Others     1.0   
 White X41 0.159 0.102 1.172 0.961~1.430 0.118
 Black X42 0.172 0.130 1.188 0.920~1.532 0.186
N stage a (as dummy variables) X5      
 N0 X50 −0.858 0.060 0.424 0.377~0.477 < 0.001
 N1 X51 −0.220 0.071 0.803 0.699~0.922 0.002
NELNs (as dummy variables) X6      
 N ≤ 6     1.0   
 6<N ≤ 12 X61 −0.121 0.058 0.886 0.790~0.993 0.038
 N>12 X62 −0.046 0.059 0.956 0.852~1.072 0.438
NPLNs (as dummy variables) X7      
 N = 0     1.0   
 1 ≤ N ≤ 3 X71 0.698 0.054 2.009 1.808~2.234 < 0.001
 N ≥ 4 X72 0.862 0.074 2.367 2.046~2.739 < 0.001
Surgery type (as dummy variables) X8      
 SLET     1.0   
 LET X81 −0.242 0.086 0.785 0.664~0.929 0.005
 PET X82 0.088 0.109 1.092 0.882~1.353 0.420
Primary site (as dummy variables) X9      
 Others X90 −0.239 0.160 0.788 0.576~1.078 0.136
 UL X91 −0.114 0.052 0.892 0.806~0.987 0.028
 ML X92 −0.273 0.114 0.761 0.609~0.952 0.017
Histological grade (as dummy variables) X10      
 I     1.0   
 II X101 0.551 0.096 1.736 1.437~2.097 < 0.001
 III X102 0.834 0.095 2.301 1.909~2.775 < 0.001
 IV X103 0.998 0.161 2.712 1.977~3.722 < 0.001
Histology (as dummy variables) X11      
 Others     1.0   
 AC X111 0.197 0.063 1.217 1.076~1.377 0.002
 S X112 0.379 0.068 1.462 1.280~1.669 < 0.001
 ASC X113 0.588 0.134 1.801 1.385~2.342 < 0.001
 BAA X114 −0.304 0.156 0.738 0.543~1.002 0.051
Marital status (as dummy variables) X12      
 Others X120 −0.057 0.216 0.945 0.618~1.444 0.793
 Single (never married) X121 −0.258 0.092 0.773 0.645~0.926 0.005
 Married X122 −0.286 0.066 0.751 0.660~0.855 < 0.001
 Divorced X123 −0.290 0.090 0.749 0.627~0.894 0.001
Tumor extensiona (as dummy variables) X13      
 T1a ss     1.0   
 T2 Visc PI X131 0.114 0.082 1.121 0.954~1.317 0.166
 T2 Centr X132 0.353 0.085 1.424 1.206~1.680 < 0.001
 T3 Inv X133 0.809 0.196 2.247 1.529~3.300 < 0.001
 T3 Satell X134 0.514 0.092 1.672 1.395~2.002 < 0.001
Tumor sizea (as dummy variables) X14      
 T1a ≤ 1(T ≤ 1)     1.0   
 T1b>1–2(1<T ≤ 2) X141 0.016 0.172 1.016 0.725~1.425 0.927
 T1c>2–3(2<T ≤ 3) X142 0.361 0.169 1.434 1.030~1.997 0.033
 T2a>3–4(3<T ≤ 4) X143 0.584 0.170 1.793 1.286~2.501 0.001
 T2b>4–5(4<T ≤ 5) X144 0.585 0.174 1.794 1.276~2.523 0.001
 T3>5–7(5<T ≤ 7) X145 0.664 0.174 1.943 1.382~2.732 < 0.001
  1. Abbreviations: B Regression coefficient, SE Standard error, RR Relative risk, CI Confidence interval, NELNs Number of examined regional lymph nodes, NPLNs Number of positive regional lymph nodes, SLET Sublobectomy, LET Lobectomy, PET Pneumonectomy, UL Upper lobe, ML Middle lobe, LL Lower lobe, I Well differentiated, II Moderately differentiated, III Poorly differentiated, IV Undifferentiated, AC Adenocarcinoma, S Squamous carcinoma, ASC Adenosquamous carcinoma, BAA Bronchioalveolar adenocarcinoma
  2. a According to the eighth edition AJCC/UICC stage classification for NSCLC.