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Table 2 Univariate analysis of the Cox proportional hazard regression model of resected T1-3N0 − 2 M0 NSCLC

From: RNSCLC-PRSP software to predict the prognostic risk and survival in patients with resected T1-3N0–2 M0 non-small cell lung cancer

Factors

Variates

b

SE

RR

95%CI

P

Gender

X1

0.363

0.049

1.438

1.307~1.582

< 0.001

Age

X2

−0.354

0.050

0.702

0.637~0.774

< 0.001

Laterality

X3

− 0.009

0.049

0.991

0.900~1.091

0.858

Race (as dummy variables)

X4

     

 Others

   

1.0

  

 White

X41

0.159

0.102

1.172

0.961~1.430

0.118

 Black

X42

0.172

0.130

1.188

0.920~1.532

0.186

N stage a (as dummy variables)

X5

     

 N0

X50

−0.858

0.060

0.424

0.377~0.477

< 0.001

 N1

X51

−0.220

0.071

0.803

0.699~0.922

0.002

NELNs (as dummy variables)

X6

     

 N ≤ 6

   

1.0

  

 6<N ≤ 12

X61

−0.121

0.058

0.886

0.790~0.993

0.038

 N>12

X62

−0.046

0.059

0.956

0.852~1.072

0.438

NPLNs (as dummy variables)

X7

     

 N = 0

   

1.0

  

 1 ≤ N ≤ 3

X71

0.698

0.054

2.009

1.808~2.234

< 0.001

 N ≥ 4

X72

0.862

0.074

2.367

2.046~2.739

< 0.001

Surgery type (as dummy variables)

X8

     

 SLET

   

1.0

  

 LET

X81

−0.242

0.086

0.785

0.664~0.929

0.005

 PET

X82

0.088

0.109

1.092

0.882~1.353

0.420

Primary site (as dummy variables)

X9

     

 Others

X90

−0.239

0.160

0.788

0.576~1.078

0.136

 UL

X91

−0.114

0.052

0.892

0.806~0.987

0.028

 ML

X92

−0.273

0.114

0.761

0.609~0.952

0.017

Histological grade (as dummy variables)

X10

     

 I

   

1.0

  

 II

X101

0.551

0.096

1.736

1.437~2.097

< 0.001

 III

X102

0.834

0.095

2.301

1.909~2.775

< 0.001

 IV

X103

0.998

0.161

2.712

1.977~3.722

< 0.001

Histology (as dummy variables)

X11

     

 Others

   

1.0

  

 AC

X111

0.197

0.063

1.217

1.076~1.377

0.002

 S

X112

0.379

0.068

1.462

1.280~1.669

< 0.001

 ASC

X113

0.588

0.134

1.801

1.385~2.342

< 0.001

 BAA

X114

−0.304

0.156

0.738

0.543~1.002

0.051

Marital status (as dummy variables)

X12

     

 Others

X120

−0.057

0.216

0.945

0.618~1.444

0.793

 Single (never married)

X121

−0.258

0.092

0.773

0.645~0.926

0.005

 Married

X122

−0.286

0.066

0.751

0.660~0.855

< 0.001

 Divorced

X123

−0.290

0.090

0.749

0.627~0.894

0.001

Tumor extensiona (as dummy variables)

X13

     

 T1a ss

   

1.0

  

 T2 Visc PI

X131

0.114

0.082

1.121

0.954~1.317

0.166

 T2 Centr

X132

0.353

0.085

1.424

1.206~1.680

< 0.001

 T3 Inv

X133

0.809

0.196

2.247

1.529~3.300

< 0.001

 T3 Satell

X134

0.514

0.092

1.672

1.395~2.002

< 0.001

Tumor sizea (as dummy variables)

X14

     

 T1a ≤ 1(T ≤ 1)

   

1.0

  

 T1b>1–2(1<T ≤ 2)

X141

0.016

0.172

1.016

0.725~1.425

0.927

 T1c>2–3(2<T ≤ 3)

X142

0.361

0.169

1.434

1.030~1.997

0.033

 T2a>3–4(3<T ≤ 4)

X143

0.584

0.170

1.793

1.286~2.501

0.001

 T2b>4–5(4<T ≤ 5)

X144

0.585

0.174

1.794

1.276~2.523

0.001

 T3>5–7(5<T ≤ 7)

X145

0.664

0.174

1.943

1.382~2.732

< 0.001

  1. Abbreviations: B Regression coefficient, SE Standard error, RR Relative risk, CI Confidence interval, NELNs Number of examined regional lymph nodes, NPLNs Number of positive regional lymph nodes, SLET Sublobectomy, LET Lobectomy, PET Pneumonectomy, UL Upper lobe, ML Middle lobe, LL Lower lobe, I Well differentiated, II Moderately differentiated, III Poorly differentiated, IV Undifferentiated, AC Adenocarcinoma, S Squamous carcinoma, ASC Adenosquamous carcinoma, BAA Bronchioalveolar adenocarcinoma
  2. a According to the eighth edition AJCC/UICC stage classification for NSCLC.