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Table 2 Co-conservation class comparison table. P-values for comparisons of the distributions of coevolution scores for each possible pairing of co-conservation classes of eQTL interactions (calculated using the two-sided KS-test)

From: Characterizing human genomic coevolution in locus-gene regulatory interactions

Class 1 Class 2 p-value
High conservation SNP High conservation SNP  
High conservation target Low conservation target p<1.045×10−6
High conservation SNP Low conservation SNP  
High conservation target High conservation target p<1.11×10−15
High conservation SNP Low conservation SNP  
High conservation target Low conservation target p<2.2×10−16
High conservation SNP Low conservation SNP  
Low conservation target High conservation target p<8.946×10−9
High conservation SNP Low conservation SNP  
Low conservation target Low conservation target p<2.2×10−16
Low conservation SNP Low conservation SNP  
High conservation target Low conservation target p<2.2×10−16