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Table 4 Top 10 differentially represented prescriptions during the 5 years prior to diagnosis of substance abuse (ranked by odds ratio)

From: Predicting opioid dependence from electronic health records with machine learning

Prescription

Odds ratio

p-value (Bonferroni-corrected)

Methadone

45.956

0

Nicotine

26.239

0

Thiamine

12.861

1.58E-277

quetiapine

11.553

3.27E-241

Trazodone

9.863

0

Clonazepam

8.38

7.21E-165

Haloperidol

6.82

8.28E-178

Folic Acid

5.28

5.03E-202

Lorazepam

4.745

2.02E-231

Ibuprofen

4.64

2.58E-202