Application of an interpretable classification model on Early Folding Residues during protein folding

Table 1 Denomination and short description of the 27 features of the dataset for individual residues classification

Feature	Description
e	Computed energy values
ePred	Predicted energy values
SecSize	Size of the surrounding secondary structure elements
LF	Fraction of surrounding unordered secondary structure elements
Rasa	Relative accessible surface area
PlipLC	Absolute count of local PLIP contacts
PlipHbLC	Absolute count of local PLIP hydrogen bonds
PlipHpLC	Absolute count of local PLIP hydrophobic interactions
PlipBbLC	Absolute count of local PLIP backbone contacts
PlipLR	Absolute count of long-range PLIP contacts
PlipHbLR	Absolute count of long-range PLIP hydrogen bonds
PlipHpLR	Absolute count of long-range PLIP hydrophobic interactions
PlipBbLR	Absolute count of long-range PLIP backbone contacts
PlipBN	Betweenness using all PLIP contacts
PlipCL	Closeness using all PLIP contacts
PlipCC	Clustering coefficient using all PLIP contacts
PlipHbBN	Betweenness using PLIP hydrogen bonds
PlipHbCL	Closeness using PLIP hydrogen bonds
PlipHbCC	Clustering coefficient using PLIP hydrogen bonds
PlipHpBN	Betweenness using PLIP hydrophobic interactions
PlipHpCL	Closeness using PLIP hydrophobic interactions
PlipHpCC	Clustering coefficient using PLIP hydrophobic interactions
ConvBN	Betweenness using the distance-based contact definition
ConvCL	Closeness using the distance-based contact definition
ConvCC	Clustering coefficient using the distance-based contact definition
PlipNC	Distinct neighborhood count using all PLIP contacts
ConvNC	Distinct neighborhood count using the distance-based contact definition