Combining DNA methylation and RNA sequencing data of cancer for supervised knowledge extraction

Table 13 Timing of the CAMUR executions, number of iterations and execution mode

Experiment	Cancer	CAMUR_time	Iterations	Mode
RNA sequencing	BRCA	14d:20h:59m:20s	60	Loose
	THCA	05d:04h:00m:51s	100	Loose
	KIRP	00d:00h:01m:22s	100	Loose
DNA methylation	BRCA	29d:00h:21m:19s	44	Loose
	THCA	29d:00h:19m:52s	39	Loose
	KIRP	00d:00h:25m:51s	100	Loose
Combined	BRCA	29d:20h:21m:25s	7	Loose
	THCA	07d:20h:53m:16s	100	Loose
	KIRP	00d:01h:34m:08s	100	Loose

We specified different maximum number of iterations according to the computation time, 80% as minimum threshold value for the classification reliability, and loose as execution mode. It is worth noting that only 7 iterations in 29 days have been performed for the combined matrix of BRCA, because the extracted classification models are composed of a high number of genes

ISSN: 1756-0381