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Table 1 List of prioritized putative regulatory SNPs

From: Functional relevance for central cornea thickness-associated genetic variants by using integrative analyses

Variant Chr Position LD (r2) Lead SNP Ref Alt CADD GWAVA Eigen-PC Genes
rs2307121 5 65,329,685 1 rs2307121 C T 15.53 0.57 1.76 ADAMTS6
rs2393729 10 62,077,257 0.98 rs7090871 C T 13.08 0.41 2.05 ARID5B
rs2721051 13 40,536,747 1 rs2721051 C T 11.62 0.58 0.65 FOXO1
rs4843047 15 85,316,545 0.83 rs6496932 G A 10.22 0.43 0.67 AKAP13
rs57817160 2 227,314,522 0.92 rs7606754 G A 16.96 0.69 0.91 COL4A3
rs59257065 2 227,314,612 0.91 rs7606754 C T 15.72 0.64 0.91 COL4A3
rs6443477 3 177,590,145 0.99 rs7620503 A C 14.6 0.57 1.70 TBL1XR1, KCMB2
rs6693322 1 36,099,761 0.8 rs96067 T C 10.78 0.49 1.26 COL8A2
rs6769466 3 177,590,226 0.99 rs7620503 G A 15.53 0.55 1.72 TBL1XR1, KCMB2
rs6862857 5 65,334,310 1 rs2307121 G C 13.57 0.58 1.54 ADAMTS6
  1. Position (hg19). Ref: Reference allele. Alt: Alternative allele. Cutoff: CADD≥10, GWAVA ≥0.4 and Eigen-PC≥ 0