Skip to main content

Table 4 The most significant GO terms in datasets

From: A multi-objective gene clustering algorithm guided by apriori biological knowledge with intensification and diversification strategies

Dataset

Cluster

Significant GO term

p-value

Arabidopsis

Cluster 1

Response to wounding(GO:0009611)

3.63E-16

  

Cellular biogenic amine metabolic process(GO:0006576)

1.00E-14

  

Cellular amine metabolic process(GO:0044106)

1.62E-14

 

Cluster 2

Lipid catabolic process(GO:0016042)

1.91E-09

  

Response to wounding(GO:0009611)

9.68E-09

  

Phenylpropanoid metabolic process(GO:0009698)

7.61E-08

 

Cluster 3

Response to organonitrogen compound(GO:0010243)

5.36E-11

  

Response to chitin(GO:0010200)

9.51E-10

  

Jasmonic acid mediated signaling pathway(GO:0009867)

3.03E-09

 

Cluster 4

Jasmonic acid biosynthetic process(GO:0009695)

7.76E-04

  

Jasmonic acid metabolic process(GO:0009694)

1.08E-03

  

Lipid oxidation(GO:0034440)

1.35E-03

Cell cycle

Cluster 1

Positive regulation of transport(GO:0051050)

1.84E-04

  

Regulation of transport(GO:0051049)

2.93E-03

  

Regulation of localization(GO:0032879)

3.39E-03

 

Cluster 2

Cell cycle(GO:0007049)

8.13E-17

  

Cell division(GO:0051301)

3.26E-16

  

Cell cycle process(GO:0022402)

2.30E-14

 

Cluster 3

Cell cycle phase(GO:0022403)

2.34E-10

  

Mitotic interphase(GO:0051329)

2.71E-10

  

Interphase(GO:0051325)

2.71E-10

 

Cluster 4

DNA replication(GO:0006260)

1.24E-16

  

DNA metabolic process(GO:0006259)

4.36E-16

  

Cell cycle(GO:0007049)

1.29E-11

Sporulation

Cluster 1

Glucose metabolic process(GO:0006006)

3.69E-08

  

Carbohydrate metabolic process(GO:0005975)

1.04E-07

  

Hexose metabolic process(GO:0019318)

2.49E-07

 

Cluster 2

Oxoacid metabolic process(GO:0043436)

1.76E-05

  

Organic acid metabolic process(GO:0006082)

1.80E-05

  

Monocarboxylic acid transport(GO:0015718)

4.42E-05

 

Cluster 3

Cell cycle process(GO:0022402)

2.76E-19

  

Cell cycle(GO:0007049)

5.83E-19

  

Anatomical formation in morphogenesis (GO:0048646)

6.88E-19

 

Cluster 4

Translation(GO:0006412)

1.03E-28

  

Ribosome biogenesis(GO:0042254)

1.84E-08

  

Ribonucleoprotein complex biogenesis(GO:0022613)

6.70E-08

Serum

Cluster 1

Mitotic recombination(GO:0006312)

1.55E-11

  

G2/M transition of mitotic cell cycle(GO:0000086)

1.68E-09

  

Chromosome segregation(GO:0007059)

1.74E-09

 

Cluster 2

Cellular response to zinc ion(GO:0071294)

5.25E-08

  

Striated muscle cell differentiation(GO:0051146)

5.98E-07

  

Response to zinc ion(GO:0010043)

1.26E-06

 

Cluster 3

Cholesterol metabolic process(GO:0008203)

7.46E-14

  

Cholesterol biosynthetic process(GO:0006695)

1.39E-13

  

Sterol biosynthetic process(GO:0016126)

2.95E-13

 

Cluster 4

Multi-multicellular organism process(GO:0044706)

8.55E-16

  

Regulation of smooth muscle cell proliferation(GO:0048660)

1.50E-14

  

Smooth muscle cell proliferation(GO:0048659)

1.84E-14

  1. We consider p-values <0.01 across all tests to be totally against the null hypothesis and are remarkably significant. It means that most of the genes belonging to a cluster have the same biological function detailed in the GO term